And what does Prof. dr Borut Štrukelj, mag. farm. (Faculty of Pharmacy) say about liposomes?
Do nutritional supplements manufactured using liposomal technology demonstrate an increase in the bioavailability of the medicinal substance to the body?
The liposomal form of nutritional supplements represents advanced pharmaceutical technology, which lends individual substances better protection in the intestinal tract; usually they are absorbed faster and better, thus reaching greater concentrations in the blood. Whether its bioavailability is greater or not, depends on the substance. Allow me to present two examples – vitamin C and curcumin; vitamin C (ascorbic acid) is a water-soluble vitamin and anti-oxidant prone to fast oxidation and dissolution, which is also frequently disposed to irritating the gastric and intestinal mucosa. Taken in liposomal form, it does not irritate the mucosa, it is absorbed considerably faster, and reaches high concentrations in the blood.
The study conducted by Davies and Hickey et al. demonstrated that liposomal vitamin C results in blood levels of up to 400 µmol/l, approximately two to three times greater than vitamin C levels attainable through oral administration.
The second example is curcumin. Curcumin is a highly active polyphenol, which functions very well in the intestines, scavenging oxygen free radicals and is believed to play a part in the protection against the development of cancer of the large intestine. Unfortunately, it absorbs poorly and is prone to fast metabolization. In liposomal form, curcumin passes from the intestine into the body much faster and in greater concentrations; it acts as an anti-inflammatory agent and protects the body by scavenging oxygen radicals.